RNA Metabolism in Neurological Disease
Sheraton San Diego Hotel and Marina, San Diego, CA, USA
7-8 November 2013
Submit your abstract by 31 May 2013 to be part of the program
Speakers
Keynote Speaker:
Phillip Sharp, Nobel Laureate,
Massachusetts Institute of Technology, USA
Plenary Speakers:
Nancy Bonini,
University of Pennsylvania, USA
Robert H. Brown Jr,
University of Massachusetts, USA
Don Cleveland,
University of California, San Diego, USA
Matthew Disney,
Scripps Institute, USA
Fen-Biao Gao,
University of Massachusetts Medical School, MA, USA
Aaron Gitler,
Stanford University, USA
Christian Haass,
LMU Munich, Munich, Germany
Adrian Krainer,
Cold Spring Harbor Labs, USA
Virginia Lee,
University of Pennsylvania, USA
Steven L. McKnight,
University of Texas Southwestern, USA
Roy Parker,
University of Colorado, USA
Leonard Petrucelli,
Mayo Clinic, USA
Rosa Rademakers,
Mayo Clinic, USA
Laura Ranum,
University of Florida College of Medicine, USA
Eric Ross,
Colorado State University, USA
Jeff Rothstein,
Johns Hopkins, USA
Chris Shaw,
King's College London, UK
Maurice Swanson,
University of Florida, USA
J. Paul Taylor,
St. Jude Children's Research Hospital, Memphis, USA
Conference Chairs
Fen-Biao Gao, University of Massachusetts Medical School, MA, USA
J. Paul Taylor, St. Jude Children's Research Hospital, Memphis, USA
Complex networks of RNA-protein interactions regulate post-transcriptional gene
expression. RNA metabolism is particularly complex in neurons, involving extensive
diversification of gene expression through splicing and redistribution of RNA subsets to
the distant compartments where they ultimately function. In recent years, perturbation of
RNA metabolism has emerged as a consistent underlying defect in certain neurological
diseases, suggesting that aspects of RNA metabolism that are unique to the nervous
system may also create unique vulnerabilities.
Topics include:
- Roles of RNA binding proteins and related RNA granules
- RAN translation in neurodegeneration
- Roles of microRNAs in neurodegeneration
- RNA-mediated toxicity
- Repeat expansion diseases and RNA metabolism
- Molecular pathogenesis of ALS and FTD
- Neurobiology of SMN and SMA
Please note that remaining speaking slots will be filled with talks selected from abstracts.


