: Genetics and Chemistry Sharing a Language of Discovery

RNA Metabolism in Neurological Disease

Sheraton San Diego Hotel and Marina, San Diego, CA, USA
7-8 November 2013

Submit your abstract by 31 May 2013 to be part of the program

Speakers

Keynote Speaker:
Phillip Sharp, Nobel Laureate, Massachusetts Institute of Technology, USA

Plenary Speakers:
Nancy Bonini, University of Pennsylvania, USA
Robert H. Brown Jr, University of Massachusetts, USA
Don Cleveland, University of California, San Diego, USA
Matthew Disney, Scripps Institute, USA
Fen-Biao Gao, University of Massachusetts Medical School, MA, USA
Aaron Gitler, Stanford University, USA
Christian Haass, LMU Munich, Munich, Germany
Adrian Krainer, Cold Spring Harbor Labs, USA
Virginia Lee, University of Pennsylvania, USA
Steven L. McKnight, University of Texas Southwestern, USA
Roy Parker, University of Colorado, USA
Leonard Petrucelli, Mayo Clinic, USA
Rosa Rademakers, Mayo Clinic, USA
Eric Ross, Colorado State University, USA
Jeff Rothstein, Johns Hopkins, USA
Chris Shaw, King's College London, UK
Maurice Swanson, University of Florida, USA
J. Paul Taylor, St. Jude Children's Research Hospital, Memphis, USA

Conference Chairs

Fen-Biao Gao, University of Massachusetts Medical School, MA, USA
J. Paul Taylor, St. Jude Children's Research Hospital, Memphis, USA

Complex networks of RNA-protein interactions regulate post-transcriptional gene expression. RNA metabolism is particularly complex in neurons, involving extensive diversification of gene expression through splicing and redistribution of RNA subsets to the distant compartments where they ultimately function. In recent years, perturbation of RNA metabolism has emerged as a consistent underlying defect in certain neurological diseases, suggesting that aspects of RNA metabolism that are unique to the nervous system may also create unique vulnerabilities.

Topics include:

  • Roles of RNA binding proteins and related RNA granules
  • RAN translation in neurodegeneration
  • Roles of microRNAs in neurodegeneration
  • RNA-mediated toxicity
  • Repeat expansion diseases and RNA metabolism
  • Molecular pathogenesis of ALS and FTD
  • Neurobiology of SMN and SMA

Submit your abstract by 31 May 2013

Please note that remaining speaking slots will be filled with talks selected from abstracts.

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Organized by

Elsevier

Supporting Publications

Brain Research
Brain Research
Conference Awards